World Library  


Add to Book Shelf
Flag as Inappropriate
Email this Book

Plos Genetics : Phosphorylation-dependent Differential Regulation of Plant Growth, Cell Death, and Innate Immunity by the Regulatory Receptor-like Kinase Bak1, Volume 7

By Guttman, David S.

Click here to view

Book Id: WPLBN0003931779
Format Type: PDF eBook :
File Size:
Reproduction Date: 2015

Title: Plos Genetics : Phosphorylation-dependent Differential Regulation of Plant Growth, Cell Death, and Innate Immunity by the Regulatory Receptor-like Kinase Bak1, Volume 7  
Author: Guttman, David S.
Volume: Volume 7
Language: English
Subject: Journals, Science, Genetics
Collections: Periodicals: Journal and Magazine Collection (Contemporary), PLoS Genetics
Historic
Publication Date:
Publisher: Plos

Citation

APA MLA Chicago

Guttman, D. S. (n.d.). Plos Genetics : Phosphorylation-dependent Differential Regulation of Plant Growth, Cell Death, and Innate Immunity by the Regulatory Receptor-like Kinase Bak1, Volume 7. Retrieved from http://www.nationalpubliclibrary.com/


Description
Description : Plants rely heavily on receptor-like kinases (RLKs) for perception and integration of external and internal stimuli. The Arabidopsis regulatory leucine-rich repeat RLK (LRR-RLK) BAK1 is involved in steroid hormone responses, innate immunity, and cell death control. Here, we describe the differential regulation of three different BAK1-dependent signaling pathways by a novel allele of BAK1, bak1-5. Innate immune signaling mediated by the BAK1-dependent RKs FLS2 and EFR is severely compromised in bak1-5 mutant plants. However, bak1-5 mutants are not impaired in BR signaling or cell death control. We also show that, in contrast to the RD kinase BRI1, the non-RD kinases FLS2 and EFR have very low kinase activity, and we show that neither was able to trans-phosphorylate BAK1 in vitro. Furthermore, kinase activity for all partners is completely dispensable for the ligand-induced heteromerization of FLS2 or EFR with BAK1 in planta, revealing another pathway specific mechanistic difference. The specific suppression of FLS2- and EFR-dependent signaling in bak1-5 is not due to a differential interaction of BAK1-5 with the respective ligand-binding RK but requires BAK1-5 kinase activity. Overall our results demonstrate a phosphorylation-dependent differential control of plant growth, innate immunity, and cell death by the regulatory RLK BAK1, which may reveal key differences in the molecular mechanisms underlying the regulation of ligandbinding RD and non-RD RKs.

 

Click To View

Additional Books


  • Plos Genetics : Risk Alleles for Systemi... (by )
  • Plos Genetics : Networks of Neuronal Gen... (by )
  • Plos Genetics : a Rice Plastidial Nucleo... (by )
  • Plos Genetics : a Toxin–antitoxin System... (by )
  • Plos Genetics : Dna Methylation of the G... (by )
  • Plos Genetics : Chromatin Landscape Dict... (by )
  • Plos Genetics : Transition-transversion ... (by )
  • Plos Genetics : a Review of Family-based... (by )
  • Plos Genetics : a Targeted Constitutive ... (by )
  • Plos Genetics : Decreased Mitochondrial ... (by )
  • Plos Genetics : Repeat Associated Non-at... (by )
  • Plos Genetics : a Wnt-frz, Volume 6 (by )
Scroll Left
Scroll Right

 



Copyright © World Library Foundation. All rights reserved. eBooks from National Public Library are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.