World Library  


Add to Book Shelf
Flag as Inappropriate
Email this Book

Plos Genetics : Inter-homolog Crossing-over and Synapsis in Arabidopsismeiosis Are Dependent on the Chromosome Axis Protein Atasy3, Volume 8

By Hawley, R. Scott

Click here to view

Book Id: WPLBN0003941875
Format Type: PDF eBook :
File Size:
Reproduction Date: 2015

Title: Plos Genetics : Inter-homolog Crossing-over and Synapsis in Arabidopsismeiosis Are Dependent on the Chromosome Axis Protein Atasy3, Volume 8  
Author: Hawley, R. Scott
Volume: Volume 8
Language: English
Subject: Journals, Science, Genetics
Collections: Periodicals: Journal and Magazine Collection (Contemporary), PLoS Genetics
Historic
Publication Date:
Publisher: Plos

Citation

APA MLA Chicago

Hawley, R. S. (n.d.). Plos Genetics : Inter-homolog Crossing-over and Synapsis in Arabidopsismeiosis Are Dependent on the Chromosome Axis Protein Atasy3, Volume 8. Retrieved from http://www.nationalpubliclibrary.com/


Description
Description : In this study we have analysed AtASY3, a coiled-coil domain protein that is required for normal meiosis in Arabidopsis. Analysis of an Atasy3-1 mutant reveals that loss of the protein compromises chromosome axis formation and results in reduced numbers of meiotic crossovers (COs). Although the frequency of DNA double-strand breaks (DSBs) appears moderately reduced in Atasy3-1, the main recombination defect is a reduction in the formation of COs. Immunolocalization studies in wild-type meiocytes indicate that the HORMA protein AtASY1, which is related to Hop1 in budding yeast, forms hyper-abundant domains along the chromosomes that are spatially associated with DSBs and early recombination pathway proteins. Loss of AtASY3 disrupts the axial organization of AtASY1. Furthermore we show that the AtASY3 and AtASY1 homologs BoASY3 and BoASY1, from the closely related species Brassica oleracea, are co-immunoprecipitated from meiocyte extracts and that AtASY3 interacts with AtASY1 results suggest that AtASY3 is a functional homolog of play a key role in establishing a bias to favor inter- have a similar role in Arabidopsis. Loss of AtASY3 also transverse filament protein AtZYP1 forms small patches Atasy3-1 are found in association with the AtZYP1 patches.

 

Click To View

Additional Books


  • Plos Genetics : on the Track of Dna Meth... (by )
  • Plos Genetics : H3.3-h4 Tetramer Splitti... (by )
  • Plos Genetics : Estrogen Mediated-activa... (by )
  • Plos Genetics : Gene Duplication of the ... (by )
  • Plos Genetics : Patterning of Leaf Vein ... (by )
  • Plos Genetics : the Rose-combmutation in... (by )
  • Plos Genetics : Phased Whole-genome Gene... (by )
  • Plos Genetics : Bmp4is Essential for the... (by )
  • Plos Genetics : Thymus-associated Parath... (by )
  • Plos Genetics : Computational Prediction... (by )
  • Plos Genetics : Mapping Determinants of ... (by )
  • Plos Genetics : Bulk Segregant Analysis ... (by )
Scroll Left
Scroll Right

 



Copyright © World Library Foundation. All rights reserved. eBooks from National Public Library are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.